Accurate Extraction of Nanometer Distances in Multimers by Pulse EPR

نویسندگان

  • Silvia Valera
  • Katrin Ackermann
  • Christos Pliotas
  • Hexian Huang
  • James H Naismith
  • Bela E Bode
چکیده

Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron-electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric systems such as membrane-embedded ion channels where data analysis is commonly hindered by multi-spin effects.

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عنوان ژورنال:

دوره 22  شماره 

صفحات  -

تاریخ انتشار 2016